A small Feb. 20, 2017, study looked at the impact of a six-week ketogenic diet on physical fitness and body composition in 42 healthy adults. The study, published in the journal Nutrition & Metabolism, found a mildly negative impact on physical performance in terms of endurance capacity, peak power and faster exhaustion. Overall, researchers concluded, “Our findings lead us to assume that a [ketogenic diet] does not impact physical fitness in a clinically relevant manner that would impair activities of daily living and aerobic training.” The “significant” weight loss of about 4.4 pounds, on average, did not affect muscle mass or function.
Blumenthal was impressed that improving diet and exercise was helpful even in this group that was at risk of developing cognitive problems and potentially even dementia. “This is not necessarily a cure, but there is currently no pharmaceutical intervention for preventing dementia,” he says. “So a starting point of improving lifestyle with exercise and perhaps diet in this group of people can have important implications down the road for their overall wellbeing.”
Long-term use of the ketogenic diet in children increases the risk of slowed or stunted growth, bone fractures, and kidney stones. The diet reduces levels of insulin-like growth factor 1, which is important for childhood growth. Like many anticonvulsant drugs, the ketogenic diet has an adverse effect on bone health. Many factors may be involved such as acidosis and suppressed growth hormone. About one in 20 children on the ketogenic diet develop kidney stones (compared with one in several thousand for the general population). A class of anticonvulsants known as carbonic anhydrase inhibitors (topiramate, zonisamide) are known to increase the risk of kidney stones, but the combination of these anticonvulsants and the ketogenic diet does not appear to elevate the risk above that of the diet alone. The stones are treatable and do not justify discontinuation of the diet. Johns Hopkins Hospital now gives oral potassium citrate supplements to all ketogenic diet patients, resulting in one-seventh of the incidence of kidney stones. However, this empiric usage has not been tested in a prospective controlled trial. Kidney stone formation (nephrolithiasis) is associated with the diet for four reasons:
Achieving ketosis is a pretty straightforward, but it can seem complicated and confusing with all of the information out there.4If you want to learn more about ketosis and the scientific process around it, you can visit a very in-depth discussion about on Dr. Peter Attia’s website. Here’s the bottom line on what you need to do, ordered in levels of importance:
The ketogenic diet has been studied in at least 14 rodent animal models of seizures. It is protective in many of these models and has a different protection profile than any known anticonvulsant. Conversely, fenofibrate, not used clinically as an antiepileptic, exhibits experimental anticonvulsant properties in adult rats comparable to the ketogenic diet. This, together with studies showing its efficacy in patients who have failed to achieve seizure control on half a dozen drugs, suggests a unique mechanism of action.
The award for the most bizarre trend in 2018 goes to this plan, which eliminates some of the healthiest foods, including fruits and veggies, nuts and seeds, beans, and grains (including whole grains). What’s left? Beef, chicken, fish, eggs, turkey, butter, milk, yogurt, and cheese. I’m typically open to any eating style that’s practiced in a healthy way, but since this plan is virtually devoid of beneficial nutrients, such as antioxidants, phytochemicals, and fiber, from plants, I can’t give it any props. And in fact, even if you’re losing weight eating nothing but animal foods, there’s still a good chance this plan will do some long-term damage. One study found that within two days of shifting to a mostly meat-and-cheese diet, your microbiome shifts in a way that promotes inflammation and intestinal disease. Plant foods are key to optimal health, as we know from studying people who live the longest, good quality lives, so let’s hope this diet trend gets dropped come the new year.
Experts now believe choices about our diet account for the vast majority of prostate cancer cases. It’s important to evaluate diet choices when it comes to risk of prostate cancer. Scientists have slowly uncovered a list of cancer super foods and supplements to optimize in your diet while also discovering foods and supplements that could actually contribute to cancer risk and aggression.
Thiamin: Also known as vitamin B1, thiamin is involved in nervous-system and muscle functioning, the flow of electrolytes in and out of nerve and muscle cells, carbohydrate metabolism, and the production of hydrochloric acid. Very little thiamin is stored in the body, so depletion can occur in a little as 14 days. Chronic alcohol intake and an inadequate diet can lead to a thiamin deficiency. Beriberi is the deficiency disease for thiamin. Sources of thiamin are pork chops, sunflower seeds, green peas, baked potatoes, and enriched and whole grain cereals and pastas.
It seems like an easy diet win: Skip breakfast and you'll lose weight. Yet many studies show the opposite can be true. Not eating breakfast can make you hungry later, leading to too much nibbling and binge eating at lunch and dinner. To lose weight -- and keep it off -- always make time for a healthy morning meal, like high-fiber cereal, low-fat milk, and fruit.